Researcher - Cystic fibrosis

Imperial College London

London, UK

 

Description

 

The Department of Gene Therapy at the National Heart and Lung Institute wishes to appoint a Research Technician to support a large cystic fibrosis gene therapy clinical trial programme. The Department is a multi-disciplinary research team and is part of the UK Cystic Fibrosis Gene Therapy Consortium (http://www.cfgenetherapy.org.uk/). The Consortium consists of over 60 scientists, clinicians, students and professionals allied to medicine across three sites in the UK.

 

Requirements

 

You must have excellent laboratory skills, preferably in molecular, biochemical and cell culture techniques. Good record keeping, written and verbal communication skills, analytical and problem solving abilities, and a proven ability to complete projects and work to deadlines are required. The post also requires flexible working hours at times.

 

Cell and Developmental Biology

Centre for Genomic Regulation

Barcelona, Spain

 

Description

 

The Centre for Genomic Regulation (CRG, http://www.crg.eu), a leading Institute in Genomics Research, is recruiting a junior group leader in the Cell and Developmental Biology program. The CRG includes 5 research programs (Gene Regulation, Stem Cells & Cancer; Cell & Developmental Biology; Systems Biology; Genes & Disease; and Bioinformatics & Genomics) and has a partnership with the EMBL through the Systems Biology Program. Scientists at the CRG have access to state-of-the-art core facilities including genomics and next generation sequencing instruments, bioinformatics, proteomics, advanced optical microscopy, FACS, robotics, and a modern animal house. The Cell and Developmental Biology program is coordinated by Vivek Malhotra, and includes a senior scientist (Isabelle Vernos) and three junior group leaders (Manuel Mendoza, Jerome Solon and Pedro Carvalho). Our aim is to recruit at least one new junior group leader that complements the ongoing research efforts with an interest in human pathologies due to defects in cell compartmentation, cytoskeletal dynamics and tissue morphogenesis.

 

PhD - Quantitative behavioural neuroscience

Centro de Regulación Genómica

Barcelona, Spain

 

Description

 

We are looking for a highly motivated researcher interested in quantitative behavioural neuroscience. One position is available to conduct a Ph.D. in the laboratory of Dr. Matthieu Louis (CRG, Barcelona, Spain). The successful candidate will join the Marie-Curie Initial Training Network FLiACT for Drosophila system neuroscience. The aim of FLiACT is to elucidate how circuit-function relationships are genetically encoded and how circuit computation controls behaviour. The FLiACT network is composed of 12 partners across Europe together with the Janelia Farm Research Campus (www.fliact.eu). The main research interest of the Louis lab is to clarify the link between sensory coding, neural circuits and behaviour. We are following a systems approach to understand how odour tracking comes about in terms of neural computation in the Drosophila larva. In previous work, we have established larval chemotaxis as a paradigm to dissect the molecular and cellular bases of sensorimotor integration and decision making in a genetic model organism. We take advantage of optogenetics to create virtual olfactory realities where quantitative models about the mechanisms controlling chemotaxis can be tested and refined.

 

Computational Biology

IMIM-UPF

Barcelona, Spain

 

Description

 

We seek candidates to apply for an advanced research position at GRIB (IMIM-UPF) in the competitive call “TECNIOSPRING” co-funded by the 7th Framework Program of the EU and the Catalan Government. Candidates should have at least nine years’ experience working on research or alternatively, a doctorate plus five years of postdoctoral experience. Additionally, one year experience in applied research or technology transfer is required. Experience in the management of research groups and/ or working in the private sector will be an advantage. This call is open to all nationalities and aims to attract research talent from abroad so it is mandatory that candidates should not have worked or lived in Spain for more than twelve months in the period from April 2010 to April 2012. The successful applicant is expected to develop a project focused on applied research and/ or technology transfer in one of the research areas of GRIB:

 

• Computational Genomics

• Structural Bioinformatics

• Computational Biophysics

• Chemogenomics

• Computer Assisted Drug Design

• Integrative Biomedical Informatics

 

PhD - Plant responses to light

Centro de Investigación en Agriogenómica, CRAG

Bellaterra, Spain

 

Description

 

A PhD position is available in the laboratory of Dra. Elena Monte (www.montelab.org) at the CRAG Institute in Barcelona, Spain to study the mechanisms underlying plant responses to light. The project combines the use of Molecular, Cellular, Genomic and Genetic approaches to elucidate the role of the transcription factor PIF3 in plant growth and development. We are seeking highly motivated and outstanding students with a background in Biological Sciences, Biochemistry or similar.

 

Applications

 

If interested, please submit your application to elena.monte@cragenomica.es and

http://www.cragenomica.es/jobs/jobs.php?id=107

 

www.cragenomica.es

PhD - Genomic regulation

Centro de Regulación Genómica, CRG

Barcelona, Spain

 

Description

 

The 4 year International PhD Programme “la Caixa” / Centre de Regulació Genòmica (CRG) provides highly talented Phd students with the opportunity to carry out research at one of the first class research centers in Europe, the Centre for Genomic Regulation (CRG). The aim of the program is to nourish the potential of selected fellows to become excellent and independent researchers. We encourage applications from highly talented and motivated scientists with outstanding qualifications. Successful candidates will join research groups with top-level scientists and will carry out their research in the following areas of biomedical sciences:

 

•Bioinformatics and Genomics

•Cell and Developmental Biology

•Gene Regulation, Stem Cells and Cancer

•Systems Biology

 

Biomedical research - 9 vacancies

Centre for Biomedical Research of the Canary Islands

La Laguna, Tenerife, Spain

 

Description

 

We are seeking for candidates to apply for 9 researcher vacacnies in the newly created Centre for Biomedical Research of the Canary Islands (Cibican) at the University of La Laguna. The contract time will be 34 months. The positions could be extended for one additional year, depending on scientific production and budget availability. The selected candidates will be incorporated into a recently funded FP7-REGPOT project (Improving Biomedical Research and Innovation in the Canary Islands: FP7-REGPOT-2012-CT2012-316137-IMBRAIN). The employed researchers will join any of the below listed research programmes and develop their research in one of the related lines, which should be addressed by their submitted proposal:

 

- Chronic and Infectious Diseases Associated with Aging and Affecting Life Quality:

   a Basic and/or clinical and translational research on chronic or infectious diseases or diseases with an immunological basis.

- Brain Diseases and Related Disorders: 

   a Neurobiology of neurodegenerative diseases;

   b Pathophysiology of the neuron and of signal transduction in excitable cells;

   c Genetic background of neurological diseases.

- Rare Diseases and Those with a Genetic Basis:

   a Molecular biology and genetics of cancer in human and in model organisms;

   b Molecular biology and genetics of rare diseases;

   c Bioinformatics, genomics and/or proteomics;

   d Biocomputing and systems biology.

- Medicinal Chemistry:

   a Nuclear magnetic resonance, structural characterisations and/or microcalorimetry;

   b Preparation of biomolecules and biomaterials.

- Social Implications of Health Issues:

   a Research on economic evaluation of healthcare technologies.

 

PhD y PostDoc - Regulación de la expresión génica y cáncer

Centro de Investigaciones Genómicas y Oncológicas

Granada, Spain

Descripción

Nuestro laboratorio estudia el papel de los microRNAs, y los complejos remodeladores de cromatina en el contexto del cáncer. Está situado en un nuevo centro de investigación excelentemente equipado: El Centro de Investigaciones Genómicas y Oncológicas (www.genyo.es) situado en Granada. El grupo está financiado por proyectos competitivos, nacionales, de la comunidad europea, e internacionales y trabajos recientes de miembros del grupo se han publicado en revistas de relevancia como Nature, Cell Reports, Human Molecular Genetics, Oncogene, etc.

Se buscan investigadores predoctorales y postdoctorales para incorporarse al laboratorio de "regulación de la expresión génica y cáncer". Se requieren investigadores con los siguientes perfiles:

- Investigador postdoctoral. Se busca candidato para solicitar un contrato Juan de la Cierva. Los candidatos deben tener al menos una publicación internacional como primer autor y experiencia en biología molecular y cultivos celulares.

- Investigador predoctoral para solicitar una beca FPI concedida a nuestro grupo. Su formación básica tiene que estar relacionada con las licenciaturas de Biología, Bioquímica, Biotecnología o grados afines. Se valorará el expediente académico, capacidad de trabajo, ambición y buen dominio del inglés. Los candidatos para el programa de 2013 FPI son aceptados.

PostDoc - Caracterización funcional de las oncoproteínas Vav

Centro de Investigacion del Cancer

Salamanca, Spain

Descripción

Nuestro grupo de investigación está buscando un/a DOCTOR/A para solicitar un contrato JUAN DE LA CIERVA correspondiente a la convocatoria de 2012. El plazo de solicitud de estos contratos finaliza el 29 de noviembre de 2012. Información sobre el programa Juan de la Cierva puede encontrarse en el BOE de 24 de octubre de 2012 (nº 256, págs. 75232-75290) y en la página web del Ministerio de Economía y Competitividad español.

El investigador seleccionado trabajará en la caracterización funcional de las oncoproteínas Vav, un grupo de proteínas implicadas en señalización celular que juegan papeles relevantes en organización citoesquelética, mitogénesis, respuestas inmunes, cáncer y procesos fisiológicos relacionados con el sistema cardiovascular y metabólico. Otros temas posibles de trabajo son los papeles que las GTPasas de la familia Rho/Rac y Ras juegan en los procesos mencionados anteriormente. Entre otros métodos, nuestro laboratorio está usando actualmente técnicas genómicas, proteómicas, genéticas (ratones knock-out y knock-in), de Biología celular y de señalización para caracterizar la función de todas estas proteínas in vivo. Estas líneas de investigación están financiadas por proyectos de investigación del Ministerio de Economía y Competitividad, el 7º Programa Marco de la Unión Europea, la Junta de Castilla y León y la Asociación Española contra el Cáncer.

PostDoc - Impact of inflammation on hematopoiesis and cancer

Department of Cell Biology and Histology, University of Murcia

Murcia, Spain

 

Description

 

We are seeking for a highly motivated postdoctoral researcher at the group of Professor Victoriano Mulero for applying for a two-year postdoctoral contract starting May 2013. Our laboratory is studying the impact of inflammation in hematopoiesis and cancer using the zebrafish as a model. Special emphasis is given to TLR and cytokine signaling in the development of blood cells and cancer progression and aggressiveness. The methods used include in vivo imaging, gain- and loss-of-function experiments in zebrafish by classical morpholino and RNA microinjection as well as site-directed mutagenesis using zinc-finger nucleases, angiogenesis and metastasis assays, infection models, microarray analysis, as well as biochemistry and molecular biology. More details about our group can be found at: http://www.um.es/nisoft/victor1.htm.

 

Requirements

 

The successful candidate should hold a PhD in biochemistry, biology, biotechnology, medicine or equivalent. Applicants should have a strong background in at least one of the following fields: 1) zebrafish, 2) live cell imaging, 3) molecular biology, 4) immunology, 5) cancer. All nationalities are very welcome. Eligibility criteria:

 

Investigador - Separación celular, Cultivo, Criopreservación/descongelación

Universidad de Córdoba

Córdoba, Spain

 

Descripción: 

 

Separación celular; Cultivo de células mesenquimales; Criopreservación/descongelación de células; Citometría de flujo; Extracción de DNA, RNA; Diferenciación celular; Inmunocitoquímica convencional y de fluorecencia; Estudios experimentales "in vivo".  

 

Requisitos:

 

Formación posdoctoral  superior a  6 años, reglada y documentada, en Investigación Biomédica, preferiblemente en el área de células madre y  medicina regenerativa.

Estancia posdoctoral en un centro extranjero (mínimo 18 meses), en actividades preferiblemente relacionadas con la medicina regenerativa.

Acreditación oficial, como personal para llevar a cabo procedimientos en animales de experimentación (Categoría B) y como personal encargado de dirigir y diseñar los procedimientos (Categoría C).

Conocimientos de citometría de flujo.

Conocimientos de biología celular y molecular

Experiencia en manejo de animales de laboratorio.

Conocimientos de técnicas de cirugía en experimentación animal.

Experiencia en aplicación de terapia celular a animales de experimentación.

Experiencia en cultivos de células derivadas de médula ósea.

Experiencia en  inmunocitoquímica e inmunohistoquímica convencional y de fluorescencia.

Experiencia en análisis histológico.

Amplios conocimientos en microscopía óptica, confocal y electrónica.

Experiencia en técnicas de microdisección por láser y secuenciación génica.

Experiencia en: cultivos celulares, criopreservación y vitrificación celular, ensayos de migración, citometría de flujo, técnicas de transfección celular.

Conocimiento del idioma Inglés: nivel alto (hablado y escrito). Nivel de comprensión de textos científicos: alto.

Informática: Conocimientos en Técnicas de Imagen aplicadas a Biología celular, Bioestadística y programas de morfometría celular.

Participación en ensayos clínicos y/o proyectos de investigación  de Terapia Celular.

Capacidad para dirigir proyectos de investigación: Haber dirigido al menos un proyecto de investigación.

Capacidad de comunicación oral y escrita: Experiencia en presentación de resultados de forma oral y escrita en foros nacionales e internacionales.

 

PostDoc - Neuroscience 2 positions

Instituto de Neurociencias de Alicante

Alicante, Spain

 

Description:

 

We are looking for postdoctoral scientists to join our multidisciplinary team investigating cellular and molecular mechanisms controlling the development of inhibitory circuits in the cerebral cortex. Candidates should hold a PhD in neuroscience.

 

-1 postdoctoral position for candidates with background in electrophysiology. Candidates with background in electrophysiology in vivo are particularly encouraged to apply.

 

-1 postdoctoral position for candidates with  background in Molecular Biology. A good understanding of microarray analysis, cell sorting, biochemistry, cell biology, DNA technology and/or knowledge in genetic manipulation are desirable.

 

The successful applicants are expected to contribute to the analysis of genes involved in neuronal circuit function using loss and gain of function strategies combined with optogenetics in mice.

More information:

 

Funding is available for an initial period of two years, with salary according to experience.  Applications will be considered until October 15th. Applicants should send an email to Beatriz Rico (brico@umh.es) including: (1) Motivation letter (2) CV, with a separate list of publications; and (3) contact information of two persons from whom references could be requested.

PostDoc - Biología

Centro Hispano-Luso de Investigaciones Agrarias

Salamanca, Spain

 

The Genetics group of CIALE  (Centro Hispano-Luso de Investigaciones Agrarias) of the University of Salamanca is recruiting applicants for a postdoctoral fellowship through the Juan de la Cierva program (MICINN-JDC, Ministerio de economía y competitividad), opening September.   The Program supports 3 years competitive postdoctoral salary for individuals who have recently received their Ph.D. (no more than 3 years) and is open to all nationalities. We are recruiting candidates in the area of fungal genetics, molecular plant microbe interactions or fungal bioinformatics.  Possible research projects include functional genomics of fungal effectors, fungal comparative genomics, genome annotation and gene family evolution.  Interested persons should contact Michael Thon (mthon@usal.es) and include a CV.

 

More information can be obtained at the following websites:

http://bioinformatics.usal.es
http://ciale.usal.es