PhD - Farmacología & Neurociencia

Universidad Autónoma de Madrid

España

Descripción

Se ofrece contrato laboral para realizar una Tesis Doctoral dentro del -Programa de Doctorado de Farmacología y Fisiología- de la UAM con -Mención hacia la Excelencia- concedido por el Ministerio de Educación.

Area de trabajo: Receptores y canales iónicos que contribuyen al proceso de exocitosis: implicación en enfermedades neurodegenerativas.

Técnicas experimentales: “Patch-clamp”, amperometría, fluorimetría, inmunocitoquímica.

PhD - Chronic mental illness

Universidad de Santiago de Compostela

Santiago de Compostela, Spain

Closing date: 22nd February 2014.

Description

Exploring the DISC1-VGF connection in chronic mental illness One ESR Marie S. Curie training position is available at the CIMUS Biomedical Research Institute, University of Santiago de Compostela, Spain (www.usc.es/cimus), in the team of Jesús R. Requena, as part of the Marie S. Curie Initial Training Network (ITN) InSens: (www.in-sens.eu).

Responsibilities and tasks:

The broad picture of the ITN in which this research project is embedded is to establish the molecular foundations of chronic mental illness (CMI) by elucidating the molecular mechanisms of the DISC1 pathway (Korth, 2012, Prion 6:134-41). DISC1, a protein that is truncated in a Scottish family with a high prevalence of CMI, forms insoluble aggregates in a subset of cases of mental disease (Leliveld et al. 2008, J Neurosci 28:3839-45). Following these studies, we have recently discovered that DISC1 regulates the expression of VGF, a neuropeptide precursor with potent antidepressant and neurotrophic properties (manuscript submitted). Therefore, we hypothesize that some of the roles of DISC1 deficits in mental disease might be mediated by reduced expression of VGF. In this context, we aim at investigating the molecular biology of this new member of the extended DISC1 pathway using a variety of molecular, cellular and animal tools, in close collaboration with the other groups that participate in this ITN. In particular, the applicant is expected to carry out studies to elucidate the signalling pathways connecting DISC1 and VGF, to identify VGF receptors and develop receptor agonists, and to study the effect of VGF-derived peptides and VGF receptor agonists on behavioural deficits of DISC1-deficient mouse models.

PostDoc - Enfermedades neurodegenerativas y cerebrovasculares

Universidad Autonoma de Madrid

Madrid, España

Descripción

Se buscan candidatos que quieran solicitar ayudas para contratos de formación postdoctoral en el Instituto Teófilo Hernando de I+D del medicamento, Universidad Autónoma de Madrid.

Tema del trabajo: Contribución de la neuroinflamación y del estrés oxidativo en las enfermedades neurodegenerativas y cerebrovasculares. Identificación de dianas y nuevas estrategias terapéuticas en neurodegeneración e isquemia cerebral.

Lugar: Instituto Teófilo Hernando de I+D del Medicamento, Departamento de Farmacología y

Terapéutica, Facultad de Medicina (junto al Hospital La Paz), Universidad Autónoma de

Madrid.

PostDoc - Molecular mechanisms of neurodegeneration

European Neuroscience Institute 

Goettingen, Germany

Description

Postdoctoral position at European Neuroscience Institute in Germany on Molecular mechanisms of neurodegeneration resulting from synaptic defects.

The laboratory of Ira Milosevic at European Neuroscience Institute in Göttingen, Germany is currently looking for a postdoctoral researcher.

Our research focuses on the studies of synaptic vesicle dynamics and its role in synaptic physiology and neurodegenerative diseases. We employ cellular and mouse models of defective synaptic vesicle recycling and combinations of cell/molecular biology, biochemistry, electron microscopy, advanced imaging and multi-dimensional genomics. This postdoctoral position will capitalize on the preliminary data obtained through next generation sequencing of various animal models, and focus on dissecting the molecular mechanisms of defective synaptic vesicle recycling that lead to neurodegeneration, in particular to Parkinson’s disease.

The successful candidate will be an active member of a vibrant international team and will get direct supervision from the PI throughout the development of the project. The project will involve preparation of primary neuronal cultures, and molecular follow-up using advanced imaging, genomics and biochemistry.

PhD - Enfermedades neurodegenerativas

Universidad Autónoma de Madrid

Madrid, España

Descripción

Se ofrece contrato laboral para realizar una Tesis Doctoral dentro del -Programa de Doctorado de Farmacología y Fisiología- de la UAM con -Mención hacia la Excelencia- concedido por el Ministerio de Educación.

Area de trabajo: Receptores y canales iónicos que contribuyen al proceso de exocitosis:

implicación en enfermedades neurodegenerativas.

Técnicas experimentales: “Patch-clamp”, amperometría, fluorimetría, inmunocitoquímica.

PostDoc - Neuropathic pain manifestations

Laboratory of Neuropharmacology / Universitat Pompeu Fabra

Barcelona, Spain

Deadline date: 28/02/2014

Description

The Laboratory of Neuropharmacology, Universitat Pompeu Fabra, in Barcelona, Spain, seeks an outstanding scientist who has demonstrated (or has strong potential for) innovation and leadership in research, to integrate her/him in their research group which covers a broad range of topics in neuroscience.

Specific issue of the position: Development of new reliable methods to evaluate neuropathic pain manifestations and treatment and the influence of emotional traits responsible for inter‐individual variability.

Research project: The position is framed within a FP7 EC‐funded project, NeuroPain, which is coordinated by the Director of the group, Rafael Maldonado. This proposal profits from the expertise of several complementary European research groups leading behavioural, electrophysiological, genetic and clinical studies in order to generate new neuropathic pain models of high predictive value for the preclinical evaluation of novel treatments and the identification of biomarkers of inter‐individual variation and treatment effectiveness in human patients.

PostDoc - Methods to evaluate neuropathic pain manifestations

Neurophar Laboratory / Universitat Pompeu Fabra

Barcelona, Spain

Deadline: 28th February 2014.

Description

Specific issue of the position: Development of new reliable methods to evaluate neuropathic pain manifestations and treatment and the influence of emotional traits responsible for inter‐individual variability

Research project: The position is framed within a FP7 EC‐funded project,NeuroPain, which is coordinated by the Director of the group, Rafael Maldonado. This proposal profits from the expertise of several complementary

European research groups leading behavioural, electrophysiological, genetic and clinical studies in order to generate new neuropathic pain models of high predictive value for the preclinical evaluation of novel treatments and the identification of biomarkers of inter‐individual variation and treatment effectiveness in human patients.

Requirements

The candidate will be involved in the development of new reliable methods to evaluate neuropathic pain manifestations and treatment and the influence of emotional traits responsible for inter‐individual

variability. Candidates should hold (or commitment to have it before May 1, 2014) a PhD degree (Biology, Pharmacology, Neurosciences, Medicine, Psychobiology, Pharmacy or related subjects) and have a strong scientifictechnical background in experimental pain models. In particular, the desired

candidate must have an excellent knowledge of behavioural models of pain, including thermal nociceptive models (Hot‐plate, Tail‐Flick, Tail‐Immersion), neuropathic pain models (sciatic nerve ligation) and mechanical perception models (Von Frey filaments). Moreover, knowledge of other behavioural paradigms (e.g. operant, anxiety and depression models) will be an asset, as well as to master immunohistochemistry, biochemical and molecular biology techniques. She/he should be fluent in English and have an interactive personality.

More information and applications

Contract - Neurodegenerative diseases

Institut d’Investigació Biomèdica Sant Pau

Barcelona, España

Fecha límite: 10/01/2014

Descripción

Se busca candidato para un puesto de personal de apoyo a la investigación en el Institut d’Investigació Biomèdica Sant Pau, Barcelona en la categoría profesional: plaza de Técnico FP2 o titulación equivalente.

Proyecto: “Characterizing the molecular mechanisms that lead to synaptic damage in neurodegenerative diseases”. Investigador principal: Dra Olivia Belbin.

Realizará funciones de soporte técnico a la investigación, concretamente:

•       Cultivo celular: mantenimiento de líneas celulares y gestión de stocks. Preparación de cultivos neuronales de ratón.

•       Técnicas de laboratorio: transfección, ELISA, electroforesis de proteínas, biología molecular, técnicas de inmunodetección.

•       Elaboración y gestión de reactivos de laboratorio, mantenimiento de equipos, gestión de pedidos.

Requisitos

Estar en posesión del título de FP2, técnico especialista de laboratorio. El contrato (que forma parte de un proyecto financiado por el Instituto de Salud Carlos III) será de 3 años (40 horas semanales).

Se valorarán positivamente la siguiente formación y conocimientos:

•       Experiencia con cultivos de células mamíferas y transfecciones.

•       Experiencia con modelos animales, preferiblemente con la titulación apropiada.

•       Experiencia de 5 años en laboratorio.

•       Persona organizada, dinámica, analítica, con excelentes habilidades personales y capacidad de trabajo.

•       Habilidad en la gestión y mantenimiento de reactivos.

Más información y solicitudes

PhD - Neurobiología del comportamiento colectivo

Instituto Cajal (CSIC)

Madrid, España

Descripción y requisitos

Buscamos interesados en solicitar un contrato fpu para realizar un doctorado en la Neurobiologia del comportamiento colectivo.

Las normas para la solicitud las podeis encontrar en http://www.boe.es/boe/dias/2013/11/21/pdfs/BOE-A-2013-12235.pdf

Si tienes un buen expediente, un master completado y quieres combinar analisis cuantitativo, modelacion matematica y experimntos de neurobiologia, escríbeme. Licenciados en Fisica, Matemáticos, Ciencias de la Computacion y Biologos son posibles candidatos.

Puedes encontrar info sobre nuestro trabajo en el Instituto Cajal (CSIC) en www-neural-circuits.org

Más información y solicitudes

PhD - Neurobiología del desarrollo de vertebrados

Instituto Cajal, CSIC

Madrid, España

Descripción

Posibilidad de solicitar una beca predoctoral de la convocatoria FPU (https://sede.educacion.gob.es/catalogotramites/profesores/formacion/universitarios/fpu.html#pg1 )

para la realización de una Tesis Doctoral en el campo de la Neurobiología del Desarrollo de Vertebrados. El grupo está interesado en los mecanismos moleculares y celulares responsables de la neurogénesis durante el desarrollo de la médula espinal y en la etapa adulta en el hipocampo.

Requisitos

Graduados con Master reciente de cualquier área de Biomedicina (Bioquímica, Biología, Química, Farmacia…)  con expediente académico superior a 2,0 y con iniciativa, motivación y experiencia de trabajo en laboratorio.

Más información y solicitudes

PhD - Neurobiología molecular y celular

Instituto de Neurociencias y FISABIO

Alicante, España

Fecha límite: 20-12-2013

Descripción

Se ofrece un contrato para un licenciado con un Master en Biología Molecular o Neurociencias.

Lugar de trabajo: Instituto de Neurociencias de Alicante UMH-CSIC.

Objetivo final:

-Realizar una tesis doctoral en neurobiología molecular y celular.

-La tesis versará sobre el papel de la señalización axón/glia durante el proceso de mielinización y la regeneración del sistema nervioso. El proyecto está financiado por el Instituto de Salud Carlos III (PI12/00164).

Se emplearán fundamentalmente técnicas de biología molecular (clonación), genómica (DNA-microchips, Chip-seq), proteómica, transgénesis murina y cultivos celulares.

Requisitos

-Licenciados en ciencias de la vida (Biología, Química, Bioquímica, Farmacia, Medicina, Biotecnología…). El título debe haberse obtenido en los tres últimos años. Se requiere un buen expediente académico (>2,5).

-Deben haber finalizado un master oficial en el campo de la biología molecular o neurociencias.

Más información y solicitudes

PostDoc - Information processing in complex systems

IFISC, Universitat de les Illes Balears

Palma de Mallorca, Spain

Description and requirements

Starting from now, we are looking for a Post-Doc for one year, renewable for another year. Candidates with a PhD in physics, mathematics, neuroscience, or information sciences with enthusiasm to work interdisciplinary are encouraged to apply. The project will concentrate on computational aspects of information processing in the brain and complex systems in general.

More information and applications

PhD - Several fellowships in different projects

NeuroCure Cluster of Excellence 

Berlin, Germany

Closing date: January 10th, 2014

Description

The NeuroCure Cluster of Excellence invites applications for its PhD program starting in 2014 NeuroCure is an inter-institutional research network based at the Charité – Universitätsmedizin Berlin. NeuroCure partner institutions include, alongside the Charité, the Humboldt Universität zu Berlin and Freie Universität Berlin as well as the non-university institutions Max Delbrück Center for Molecular Medicine Berlin-Buch (MDC), Leibniz-Institut für Molekulare Pharmakologie (FMP) and German Rheumatism Research Centre Berlin (DRFZ).

With over 50 internationally recognized research groups, NeuroCure offers outstanding interdisciplinary training and research opportunities for national and international scientists from a wide range of academic backgrounds.

Fellowships are available in the following subject areas:

•Molecular mechanisms of nervous system development and function.

•Mechanisms of neural damage and cellular age.

•Endogenous brain protection.

•Nervous system regeneration.

•Crosstalk between nervous and immune system.

•Developmental disturbances.

•Synaptic plasticity.

More information and applications

PostDoc - Neurobiologist

Biomedical Research Foundation, Academy of Athens

Athens, Greece

Description

Neurobiologist needed to study of the rat dopaminergic nigrostriatal system following injections of Adeno-Associated Viruses that impact the CMA pathway, Reduction of Lamp2a in rat substantia nigra – assessment of impact on dopaminergic system- assessment of impact on endogenous alpha-synuclein- assessment of impact on autophagy-assessment of impact of concomitant injection of an AAV overexpressing alpha-synuclein.

Requirements

-University degree (BSc) in Life sciences.

-Advanced Degree (MSc) in Life Sciences. 

-Expertise in cellular and molecular neurobiology.

-Expertise in small animal handling.

-Expertise in using neurotropic viruses to express proteins of interest in the CNS. 

-Expertise in evaluating observed effects on histological and biochemical markers.

More information and applications

PostDoc - Computational models of memory consolidation

Centre de Recerca Matemàtica

Bellaterra (Barcelona), Spain

Description

A two-year postdoctoral position is available starting January 2014 in the computational neuroscience group at the Centre de Recerca Matemàtica in Bellaterra, Spain. This position is funded by project BFU2012-33413 from the “Ministerio de Economia y Competitividad” of the Spanish government.

During these two years, the postdoctoral researcher will work on computational models of memory consolidation in close collaboration with the principal investigator. 

Requirements

Candidates for the position should have a strong technical background, e.g. Physics, Applied Mathematics, Computer Science, and preferably some experience with modeling biological systems.

More information and applications

PostDoc - Neuroscience

Universitat Autonoma de Barcelona

Barcelona, Spain

 

Description

 

The Group of Neuroplasticity and Regeneration at the Universitat Autonoma de Barcelona is looking for applications for a predoctoral fellowship or an starting postdoctoral (less than 2 years PhD holder) fellowship. The fellowship may be renewed for up to 4 years, and is funded by an European Comission project. Our group is a multidisciplinary team investigating new strategies for regeneration and recovery of peripheral nerve and spinal cord injuries and diseases. For this project we are looking for a candidate fellow with strong interest in neuroscience and neuroprostheses, to develop innovative research on new strategies to modulate neuropathic pain by means of activity and electrical stimulation. The fellow will be mainly involved in experimental studies on rat models of neuropathic pain, performing microsurgery, electrophysiology and immunohistochemistry techniques. Testing new electronic devices for providing intraneural stimulation will be also part of the work. The European project involves also partners that will perform clinical studies for the amelioration of pain in amputees. Therefore, the fellow will be participating in a rich international and multidisciplinar environment.

 

Requirements

 

Candidates should hold a relevant Degree, Master or PhD. Prior experience in in vivo experimental research, electrophysiology, immunohistochemistry and microscopy is advantageous.

PostDoc - Assembly and Wiring of Brain Circuits

Neurobiology department, University of Massachusetts Medical School

Worcester, United States

 

Description

 

We are seeking highly motivated individuals to work on a research project focused on the assembly and wiring of brain circuits. Our laboratory is interested in the mechanisms that regulate the connectivity between neurons. We focus on the process of neuronal integration during adult neurogenesis in the olfactory bulb and hippocampus. The research combines techniques in electrophysiology, molecular biology, neuroanatomy, viral tracing, and transgenesis in rodents. Representative recent publications:

 

• Watching synaptogenesis in the adult brain. (2010) Annu Rev Neurosci. 33:131-­‐49.
• Genetically increased cell-­‐intrinsic excitability enhances neuronal integration into adult brain circuits (2010) Neuron 65:32-­‐39.
• Wandering neuronal migration in the postnatal vertebrate forebrain. (2012) J Neurosci. 32(4):1436-­‐1446.
• Increased cell-­‐intrinsic excitability induces synaptic changes in new neurons in the adult dentate gyrus that require npas4. (2013) J Neurosci. 33(18):7928-­‐40.

See:

 

http://profiles.umassmed.edu/profiles/ProfileDetails.aspx?From=SE&Person=1380

for more information

 

Requirements

 

- A Ph.D. in neuroscience or a related field is required and candidates should have a record of research excellence demonstrated by publication.

- Experience with electrophysiological recordings, developmental neuroscience or molecular neurobiology is highly desired.
- Candidates must have a strong interest to work as members of a team.
- Applicants who are motivated to develop careers as independent investigators are especially encouraged.

 

PostDoc - Biology and Health Sciences - Several positions

Department of Experimental and Health Sciences, Pompeu Fabra University

Barcelona, Spain

 

Description

 

We are looking for postdoctoral fellows willing to apply for a IEF or IIF Marie Curie postdoctoral fellowship in the Department of Experimental and Health Sciences at the Pompeu Fabra University (UPF), Barcelona, Spain. Research lines include:

 

- Cell and Molecular Biology

- Evolutionary Biology and Complex Systems

- Biomedical Informatics

- Genetics and Neurosciences

- Public Health

 

Requirements

 

The Marie Curie fellowships calls are highly competitive so only very motivated candidates with a PhD in Life Sciences and a strong CV are encouraged to apply. The UPF Research Service will provide specialized assistance in the writing and submission of applications.

 

PostDoc - Neurosciences

University of Massachusetts Medical School

United States

Description

We are seeking highly motivated individuals to work on a research project focused on the assembly and wiring of brain circuits. Our laboratory is interested in the mechanisms that regulate the connectivity between neurons.  We focus on the process of neuronal integration during adult neurogenesis in the olfactory bulb and hippocampus.  The research combines techniques in electrophysiology, molecular biology, neuroanatomy, viral tracing, and transgenesis in rodents.

Requirements

A Ph.D. in neuroscience  or a related field is required and candidates should have a record of research excellence demonstrated by publication. Experience with electrophysiological recordings, developmental neuroscience or molecular neurobiology is highly desired. Candidates must have a strong interest to work as members of a team.  Applicants who are motivated to develop careers as independent investigators are especially encouraged.