PostDoc or PhD - Computational modeler of multicellular dynamics

Centre for Genomic Regulation

Barcelona, Spain

 

Description

 

The Centre for Genomic Regulation (CRG) is an innovative center for basic research created in December 2000 by initiative of the former Department of Universities, Research and Information Society (DURSI) of the Catalan Government. The CRG is legally constituted as a non-profit foundation and has the participation from the Catalan Government through the Economy and Knowledge Department (DECO) and the Health Department (DS), as well as from the Pompeu Fabra University (UPF), and the Spanish Ministry of Science and Innovation (MICINN). It is an international biomedical research institute of excellence whose mission is to discover and advance knowledge for the benefit of society, public health and economic prosperity. James Sharpe is the acting coordinator of the EMBL-CRG Systems Biology program of the CRG, which studies many different aspects of systems biology. He is head of the laboratory for Systems Analysis of Development. We are located within the PRBB, a research park with state-of-the-art animal facilities, also including other research organisations pursuing developmental biology such as the CMBR and the UPF developmental biology department. The position will involve creating 3D Cellular Potts Models to explore two biological systems:

 

(a) The interactions of immune cells in the lymph node (T-cells and dendritic cells) during an immune response to infection. This will be done in collaboration with the laboratory of Dr. Maree at the John Innes Centre in Norwich.

(b) Elongation of the mouse limb bud during embryo development.

 

Requirements

 

- Background or extensive experience in mathematical modeling.

- Evidence of good programming skills.

- Good working knowledge of English.

 

Desirable experience:

 

- Extensive experience with Cellular Potts Models.

- Prior experience with mathematical modeling.

- Systems biology, gene regulatory networks.

- Data visualization, 2D and 3D.

- Understanding of immunology and/or cell biology.

 

More information and applications

 

- Deadline for application: 30th April 2013.

- Three year contract.

 

All applications must include:

 

- A presentation letter addressed to Dr. James Sharpe explaining motivation and scientific interests.

- A full CV including your contact details.

 

Please submit your application by email to the following address, indicating the offer reference in the subject message: rrhh@crg.eu