University of Dundee
Scotland, United Kingdom
The deadline for applications is 31st March, 2014.
Description
Early Stage Researcher – MARIE CURIE RESEARCH FELLOW
Project Name: Optical tweezers for kinetochore-microtubule interaction
Summary of Job Purpose & Principal Duties:
This is a unique and exciting opportunity to participate in a European project entitled PHOQUS:
PHOtonic tools for Quantative imaging in tissUeS. This 3-year PhD programme is a new, highly innovative scheme to train postgraduate students as truly interdisciplinary scientists either as "problem oriented physicists” or "solution oriented biologists".
The PHOQUS project will utilise the University of Dundee’s extensive and world-class expertise in Life Sciences, pioneering work in the Medical School and advanced Photonics to deliver an Innovative Doctoral Training Program directed at the development and application of novel imaging modalities to enable the quantitative investigation of biological processes from the molecular and cellular to the tissue and organ level scale. The training programme will lead automatically to advances and new knowledge on how to harness these new technologies and new strategies. The PHOQUS project is strongly interdisciplinary, with close involvement of 10 Associated Partners and 9 Academic Partners distributed over 7 European countries.
In the ESR6 project of the PHOQUS programme, a student will study dynamic kinetochore-microtubule interaction in vitro. To maintain genetic information, cells have to inherit the whole set of chromosomes when they multiply. This process relies on correct kinetochore-microtubule interaction during mitosis. The aim of the project is to reconstitute kinetochore-microtubule interaction in vitro using optical tweezers. This research will be undertaken in Prof Tomo Tanaka and Dr David McGloin’s groups in the University of Dundee, Dundee, UK. The successful candidate will also undertake short-term secondments to associate partners and collaborators.
Applicants should have a good first degree and less than 4 years research experience. Candidates with a PhD will not be eligible for this position. The first degree should be in biophysics or biochemistry. Experience of optical tweezers, single-molecule TIRF microscopy or in vitro microtubule reconstitution would be an advantage. The successful applicant will be given the opportunity to work towards the award of a PhD with the University of Dundee.
More information and applications
For informal discussions and further details, please contact Prof. Tomo Tanaka (t.tanaka@dundee.ac.uk) and Dr David McGloin (D.McGloin@dundee.ac.uk).
This is a full-time fixed-term contract for 3 years commencing June – August 2014. Successful candidates will receive a generous salary in the region of £38,000 per annum (subject to UK tax deductions) with tuition fees fully covered.
The researcher will be a Marie Curie Fellow funded by a grant under the European FP7 program.
As a requirement of the grant this position is open only to researchers not residing or having their main activity in the country of the beneficiary home organisation (i.e. UK) for more than 12 months in the last 3 years before recruitment. Please submit your application through the PHOQUS website (www.phoqus.eu).
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